1.
Indian J Exp Biol
;
1991 Mar; 29(3): 230-2
Article
in English
| IMSEAR
| ID: sea-57425
ABSTRACT
Emodin, an anthraquinone derivative, isolated from the whole plant of R. triquerta, in 15 mg/kg dose (ip) exhibited anti-inflammatory activity against carrageenin-induced pedal inflammation in rats. In the same dosage it also showed antiulcer activity against 4 hr pylorus-ligated, aspirin and immobilization stress-induced gastric ulcers in rats. It decreased acid and pepsin output and augmented mucus secretion in terms of total carbohydrate: protein ratio in the gastric juice of aspirin treated pylorus-ligated rats, indicating that the antiulcerogenic effect of emodin may be due to its effect on gastric secretion.
Subject(s)
Animals , Anti-Inflammatory Agents, Non-Steroidal , Anti-Ulcer Agents , Emodin/isolation & purification , Female , Gastric Juice/drug effects , Inflammation/prevention & control , Male , Rats , Ulcer/prevention & control
2.
Indian J Exp Biol
;
1988 Feb; 26(2): 121-4
Article
in English
| IMSEAR
| ID: sea-61647
3.
Article
in English
| IMSEAR
| ID: sea-22147